Cross Species Expression Analysis of Innate Immune Response
نویسندگان
چکیده
منابع مشابه
Cross Species Expression Analysis of Innate Immune Response
The innate immune response is the first line of host defense against infections. This system employs a number of different types of cells, which in turn activate different sets of genes. Microarray studies of human and mouse cells infected with various pathogens identified hundreds of differentially expressed genes. However, combining these datasets to identify common and unique response patter...
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MOTIVATION Many biological systems operate in a similar manner across a large number of species or conditions. Cross-species analysis of sequence and interaction data is often applied to determine the function of new genes. In contrast to these static measurements, microarrays measure the dynamic, condition-specific response of complex biological systems. The recent exponential growth in microa...
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ژورنال
عنوان ژورنال: Journal of Computational Biology
سال: 2010
ISSN: 1066-5277,1557-8666
DOI: 10.1089/cmb.2009.0147